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If I were to give a prize for the single best idea anybody ever had, I'd give it to Darwin for the idea of natural selection - ahead of Newton, ahead of Einstein - because his idea unites the two most disparate features of our universe: the world of purposeless, meaningless matter and motion, particles jostling on the one side, and the world of meaning and purpose, design on the other.
To be nobody but yourself in a world which is doing its best, night and day, to make you everybody else means to fight the hardest battle which any human being can fight, and never stop fighting.
Given the scale of life in the cosmos, one human life is no more than a tiny blip. Each one of us is a just visitor to this planet, a guest, who will only stay for a limited time. What greater folly could there be than to spend this short time alone, unhappy or in conflict with our companions? Far better, surely, to use our short time here in living a meaningful life, enriched by our sense of connection with others and being of service to them.
In order to discover whether the picture is true or false we must compare it with reality. It cannot be discovered from the picture alone whether it is true or false. There is no picture which is a priori true.
Dixit 
