The sense of the world must lie outside the world. In the world everything is as it is, and everything happens as it does happen: in it no value exists—and if it did exist, it would have no value. If there is any value that does have value, it must lie outside the whole sphere of what happens and is the case. For all that happens and is the case is accidental. What makes it non-accidental cannot lie within the world, since if it did it would itself be accidental. It must lie outside the world.
Seek out that particular mental attribute which makes you feel most deeply and vitally alive, along with which comes the inner voice which says, 'This is the real me,' and when you have found that attitude, follow it.
My lab looks at the ability of stress hormones to kill brain cells, and basically we are trying to understand on a molecular level how a neuron dies after a stroke, a seizure, Alzheimer's, brain aging, and what these stress hormones do to make it worse.
Some of us, for better or worse, develop very stable, consistent, and largely predictable machineries of self. But in others, the self machinery is more flexible and more open to unexpected turns.
Human beings are actually more closely related to the two species of chimpanzees (Pan troglodytes, the familiar chimp, and Pan paniscus, the rare, smaller pygmy chimp or bonobo) than those chimpanzees are to the other apes.
Still, it will sometimes strike a scientific man that the philosophers have been less intent on finding out what the facts are, than on inquiring what belief is most in harmony with their system.