We think the Mac will sell zillions, but we didn’t build the Mac for anybody else. We built it for ourselves. We were the group of people who were going to judge whether it was great or not. We weren’t going to go out and do market research. We just wanted to build the best thing we could build.
Lots of work has examined the genes involved, most broadly showing that variants that produce lowered dopamine signaling (less dopamine in the synapse, fewer dopamine receptors, or lower responsiveness of these receptors) are associated with sensation seeking, risk taking, attentional problems, and extroversion. Such individuals have to seek experiences of greater intensity to compensate for the blunted dopamine signaling.
Man is a mystery: if you spend your entire life trying to puzzle it out, then do not say that you have wasted your time. I occupy myself with this mystery, because I want to be a man.
Remembering that I’ll be dead soon is the most important tool I’ve ever encountered to help me make the big choices in life. Because almost everything — all external expectations, all pride, all fear of embarrassment or failure — these things just fall away in the face of death, leaving only what is truly important. Remembering that you are going to die is the best way I know to avoid the trap of thinking you have something to lose. You are already naked. There is no reason not to follow your heart.
Reason is non-negotiable. Try to argue against it, or to exclude it from some realm of knowledge, and you've already lost the argument, because you're using reason to make your case. And no, this isn't having "faith" in reason (in the same way that some people have faith in miracles), because we don't "believe" in reason; we use reason.
Christianity is not a doctrine, not, I mean, a theory about what has happened and will happen to the human soul, but a description of something that actually takes place in human life. For ‘consciousness of sin’ is a real event and so are despair and salvation through faith. Those who speak of such things (Bunyan, for instance) are simply describing what has happened to them, whatever gloss anyone may want to put on it.